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However, it is disappointing that IGF-1 has not been shown to play a very significant role in promoting tendon healing in clinical trials, which could reflect our poor understanding of the molecular mechanisms by which IGF-1 is involved in promoting tendon regenerative healing

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RHEUMATOLOGY 64 (6), 35003508

Qian L, Zhu Y, Deng C, Liang Z, Chen J, Chen Y et al (2024) Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) family in physiological and pathophysiological process and diseases

Studies suggest that supplements such as selenium, alpha-lipoic acid or N-Acetyl-Cysteine could significantly increase intracellular GSH levels